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Wellcome Trust Sanger Institute
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These resources have been reviewed and selected by STEM Learning’s team of education specialists for factual accuracy and relevance to teaching STEM subjects in UK schools.
Build a Bug Activity
This is a classroom-based activity from the Wellcome Trust Sanger Institute that allows students to explore the features of two bacterial pathogen genomes. The aim of this activity is to highlight the role of different genetic components in two closely related subspecies of Salmonella enterica, and to identify how these contribute to the bacteria’s ability to infect their hosts causing two very distinct illnesses, food poisoning and typhoid fever. The activity is suitable for GCSE and A-level students. Its supporting PowerPoint presentation can be used to discuss the role of bacteria in disease, the structure of a prokaryotic cell and how bacteria can acquire antibiotic resistance genes. The activity can be carried out using either paper-based resources or a web-based tool.
Show health and safety information
Please be aware that resources have been published on the website in the form that they were originally supplied. This means that procedures reflect general practice and standards applicable at the time resources were produced and cannot be assumed to be acceptable today. Website users are fully responsible for ensuring that any activity, including practical work, which they carry out is in accordance with current regulations related to health and safety and that an appropriate risk assessment has been carried out.
Downloads
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Presentation 5.57 MB
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Presentation notes 1.44 MB
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Information cards 217.48 KB
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Teachers' notes 2.57 MB
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Activity sheet 2.36 MB
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Activity sheet (model) 1.32 MB
Show downloads
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Presentation 5.57 MB -
Presentation notes 1.44 MB -
Information cards 217.48 KB
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Teachers' notes 2.57 MB
-
Activity sheet 2.36 MB
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Activity sheet (model) 1.32 MB
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Download all files as a .zip12.53 MB
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