Resources by Wellcome Trust Sanger Institute

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Balloon Bugs

This resource from Wellcome Trust Sanger Institute is a practical, classroom activity that allows the students to make a balloon model of a disease-causing bacterium. This illustrates its basic shape and structure. Students can choose from three bacteria species...

Build a Bug Activity

This is a classroom-based activity from the Wellcome Trust Sanger Institute that allows students to explore the features of two bacterial pathogen genomes. The aim of this activity is to highlight the role of different genetic components in two closely related subspecies of Salmonella enterica, and to identify how...

Contamination Detectives

This resource from Wellcome Trust Sanger Institute is a hands-on classroom activity for Key Stage Two students that aims to support the teaching of topics such as microbes and hand hygiene. This interactive, practical activity demonstrates how microbes, such as bacteria and viruses, can be spread through surface...

DNA

Produced by the Wellcome Trust Sanger Institute, these resources will help students to understand the structure of DNA, where it is found in cells and the function it performs. The activities include:

* Animation which 'zooms in' on a body to ultimately reveal the structure of DNA
* Activities making...

DNA Libraries: Bacterial Artificial Chromosome (BAC)

Produced by the Wellcome Trust Sanger Institute, this resource contains an overview of the techniques involved in making a BAC (Bacterial Artificial Chromosome) library. It consists of an animation that covers the key stages in the process:

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DNA Sequence Bracelets

From the Sanger Institute, this craft based activity suitable for classroom use or science festivals where students make a DNA sequence bracelet that carries part of the code of an organism such as a human, trout, chimpanzee or butterfly.

The activity reinforces the principle of complementary base pairs as...

DNA Sequencing

From the Wellcome Trust Sanger Institute, this animation shows a detailed overview of the processes involved in the dideoxy or Sanger method for sequencing DNA. This is the method used to sequence the human genome. The animation demonstrates the principles and techniques involved in the Sanger sequencing method,...

From DNA to Protein

Produced by the Wellcome Trust Sanger Institute, this animation gives an overview of the process of protein synthesis and how DNA codes for proteins. It covers the major stages of the process starting with where DNA is found in the cell and how its information is transcribed into mRNA. It then follows through the...

Function Finders *suitable for home teaching*

Produced by the Wellcome Trust Sanger Institute, in this activity students translate DNA sequences into a series of amino acids to discover which protein is coded for and its function.

Students are supplied with a worksheet with DNA sequences and a codon wheel to decode the codons into amino acids. The amino...

Genome Generation

A number of scenarios are presented to encourage debate around genome sequencing. All teaching materials are provided.

  • The interaction of genetic and environmental factors in influencing phenotype
  • Ethical implications of genetic screening

Curriculum links:

  • Sequencing...

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