This film tells the story of how DNA sequencing was used to identify the gene BRAF. Clinical researcher Ultan McDermott tells the story of how scientists at the Wellcome Trust Sanger Institute discovered a specific mutation in the BRAF gene, which is found in around half of malignant melanoma cases. He...

This resource from Wellcome Trust Sanger Institute is a practical, classroom activity that allows the students to make a balloon model of a disease-causing bacterium. This illustrates its basic shape and structure. Students can choose from three bacteria species...

From the Integrating Mathematical Problem Solving project by Mathematics in Education and Industry (MEI), this activity for post-16 students demonstrates that if a link is suspected between a risk factor and an illness, statistical methods can be used to test whether such a link exists. Topic areas covered are:...

In this module students will study barnacle morphology, life histories and life styles as Darwin did. He based his classification and search for a common ancestor upon his studies. Recent work using genetic and molecular evidence and scanning electron microscopy shows how some of the key difficulties in drawing the...

The Youth Grand Challenges is a new STEM competition that aims to inspire students aged 11-to-19.  This resource provides a selection of ideas for research or practical projects on the subect of the spread of disease.

Curriculum links include pathogens, bacteria, epidemics, pandemics, malaria, water borne...

This is a classroom-based activity from the Wellcome Trust Sanger Institute that allows students to explore the features of two bacterial pathogen genomes. The aim of this activity is to highlight the role of different genetic components in two closely related subspecies of Salmonella enterica, and to identify how...

In this activity, students create colour images from satellite data. This allows them to study how different surfaces reflect different wavelengths of light, how coloured images are created using an RGB model, and how band combinations can be chosen to examine a particular landscape effectively.

From the Integrating Mathematical Problem Solving project by Mathematics in Education and Industry (MEI), this activity for post-16 students demonstrates that the acidity of a solution depends on the number of hydrogen ions per litre; the number of hydrogen ions per litre varies so much that a logarithmic scale is...

There are two parts to the DIY Dendrometer resources: 

Part A focusses on how trees grow and their role within both the carbon cycle and the water cycle. Learners are encouraged to take part in a citizen science project which involves creating and installing a DIY...

Activities in this resource aim to:

• celebrate the achievement of completing the Human Genome project in 2003
• show the relevance of genome sequencing today
• explain the methods used for DNA sequencing, including the illumina method of rapid sequencing and the shotgun sequencing
...

This resource is designed to meet the specifications for the A-level practical endorsement in England (CPAC). However, it will make a valuable guide to dissection and scientific drawing of a flower for those following a variety of different specifications.

The ability to accurately observe, dissect and...

This resource from the Institute of Physics, describes how electrocardiagrams (ECGs) record the activity of the heart through electrodes placed on a patient's skin. The teacher's notes contain an introduction to ECGs and lesson notes for the associated PowerPoint file. A mark scheme for the worksheet is also...

There are teacher notes and student materials which describe the research into the potential effects of climate change on a Coralline algae species. Curriculum links include biodiversity, sampling techniques, student t test, Simpson’s Index, photosynthesis, climate...

This challenge, from Practical Action, requires students to design and build a model structure that will enable farmers to grow crops even in an area that may become flooded. A floating garden, built on a base of aquatic weeds, is a low cost and sustainable way of allowing people to grow vegetables. The resource...