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DNA replication theory

Diagramatic representation of the replication of DNA. This is the process by which the cell makes a copy of its existing DNA before it divides. This therefore ensures that each new cell receives a full complement of DNA. The DNA polymerase enzyme can only add new bases in the 5'-3' direction. This leads to continuous synthesis on the leading strand and short stretches of new DNA on the lagging strand. These short "Okazaki" fragments are quickly joined together by a DNA ligase enzyme.

This resource is part of the Post 16 genetics and genomics collection of resources.

Credit: Pete Jeffs, Wellcome Images


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