At GCSE, students should appreciate that enzymes are important proteins, essential for reactions to take place. They need to be able to explain the mechanism of enzyme action, including the active site, enzyme specificity and factors affecting the rate of enzymatic reactions.

Misconceptions about enzymes include the idea that enzymes work best at 370C. It is important to make students aware early on in the delivery of this topic that enzymes are found in a variety of organisms which exist in extremes of temperature and do not have a constant body temperature. To ensure that students do not refer to enzymes as "being killed" it is essential that they have an understanding of the structure and concept of an enzyme as a component within a cell so that they are comfortable referring to enzymes being denatured.

Whilst this list provides a source of information and ideas for experimental work, it is important to note that recommendations can date very quickly. Do NOT follow suggestions which conflict with current advice from CLEAPSS, SSERC or recent safety guides. eLibrary users are responsible for ensuring that any activity, including practical work, which they carry out is consistent with current regulations related to Health and Safety and that they carry an appropriate risk assessment. Further information is provided in our Health and Safety guidance.