Modern analytical techniques
Modern techniques of analysis have revolutionised the determination of the structures of organic molecules.
At A level four techniques are covered:
- thin-layer chromatography to purify compounds but can also be used to identify compounds
- mass spectrometry gives the Mr of a compound directly and high resolution mass spectrometry can also identify a compound directly from its accurate mass
- infra red spectroscopy allows rapid identification of organic functional groups
- nuclear magnet resonance spectroscopy (NMR) , both 13C and 1H, allows the molecular framework of a molecule to be deduced.
Mass spectrometry and infra red spectrosopy are normally studied in year one, whilst chromatography and NMR spectroscopy are studied in year two.
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Mass Spectroscopy *suitable for home teaching*
This series of videos and associated tasks takes a closer look at how analytical techniques are being used in an archeological context. Some of the techniques discussed are mass spectrometry, mitochondrial DNA analysis and looking at protein structure.
Molecules From the Past *suitable for home teaching*
This article explains how modern analytical techniques are being used to gather information about ancient civilisations.