Entry level mouse genetics for animal technicians and junior researchers HC554 / G01
This course is aimed at technical staff, students and researchers new to the field of mouse genetics. It covers the fundamental genetic knowledge required when working with genetically altered mice. This includes training in Mendelian gene inheritance, breeding plans, dominant and recessive alleles and mouse genetic backgrounds.
We will also cover aspects of more complex genetics including multiple allele crosses, integrity of genetic backgrounds and overviews on establishing new genetically altered lines. This is intended to inform breeding strategies and calculations rather than give a complete guide to the molecular biology.
Teaching is delivered via seminars and interactive workshops. It includes worked examples and practical sessions on how to plan, predict and interpret mouse genotypes from standard laboratory crosses or genetically altered mouse lines.
The outcomes of this course are:
- An understanding of Mendelian gene inheritance
- An ability to predict the outcomes of genetic crosses
- A working knowledge of the genetic background of mouse strains
- An understanding of how to maintain the genetic integrity of inbred lines
- The ability to plan breeding schemes
- The ability to perform multiple allele inheritance calculations
- An understanding of how Genetically Altered lines can be established from modern transgenic technologies
|Entry Level Mouse Genetics for Animal Technicians and Junior Researchers||18 March 2019 09:00-16:00|
- Lunch and refreshments will be provided, please inform us of any dietary requirements well in advance
- Please wear suitable closed toe footwear and bring any prescription safety glasses if required
- As part of this training course, the MRC wish to offer a tour of our Animal facility. Tours will take place after the course finishes at 16:00 and take approximately an hour.
- Barrier restrictions apply to certain areas in case of contact with rodents within preceding 48 hour period.
- Allergies to rodents or latex may limit participation in the tour of facilities and / or the practical components of this course.