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Populations

What’s the first thing that pops into your mind when you read the word population? Most likely it’s the ever-increasing human population on earth. The term population isn’t just used to describe humans; it includes other animals, plants and microbes too. These resources will help you learn more about how...

Health and Climate Change

Published by the Wellcome Trust, the 'Big Picture' explores issues around biology and medicine. The Earth's climate is changing ever faster, and human activities play a role in speeding up this change.

The Earth’s climate is changing. In fact, it has always been changing. What is different now is the speed...

Drugs

Published by the Wellcome Trust, the 'Big Picture' explores issues around biology and medicine. While providing immense benefits, drugs are not the perfect solution.

They only work on a proportion of patients, sometimes they harm us, and we're not very good at taking them as we should. For some diseases,...

Plants

This issue of Big Picture provides lots of interesting information about flowering plants and their uses. 

The plant hormones animation explores the action of indole-3-acetic acid (IAA) and shows how scientists used experimental evidence to explain the role of auxins in a phototrophic response.

The...

Immune System

This resource looks at several aspects of the immune system including: • The non-specific immune response • Specific immune response and antigen recognition • T cells and B cells • Autoimmune disease and allergic responses • Monoclonal antibodies • Long term immunity and vaccination There is a section which...

Inside the Brain

These resources from the Wellcome Trust explore how imaging research has changed the way we look inside one of our most fascinating organs, the brain. The accompanying lesson ideas provides related activities and ideas for investigations or extended project qualification (EPQ). There is useful background...

Enzymes are Proteins

Enzymes are proteins that speed up the reactions by acting as catalysts. They increase the rate of reaction without being consumed or permanently altered by themselves. In Greek enzymes are divided into sections “En” which means “in” and second part is “zyme” means living. The study of enzymes is known as...

Electrophoresis gel with annotation

Di-deoxy sequencing is a way to determine the order of bases (A,C,G and T) in a piece of DNA. A set of 4 lanes (one for each base) is needed to sequence any given piece of DNA. Wherever a black
band appears in a particular lane that base is present. By reading off the order of bands across the four lanes the...

Di-deoxy sequencing gel with annotation

Di-deoxy sequencing is a way to determine the order of bases (A,C,G and T) in a piece of DNA.  A set of 4 lanes (one for each base) is needed to sequence any given piece of DNA. Wherever a black band appears in a particular lane that base is present. By reading off the order of bands across the four lanes the...

Automated DNA sequencing output

The output from an automated DNA sequencing robot used by the Human Genome Project to determine the complete human DNA sequence. Each peak shows the presence of a particular base. The sequence of bases in a given stretch of DNA can therefore be read from the order of the peaks along the trace. The sequences of...

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