Alfie's Story

Alfie, aged 14, was born with chronic granulomatous disorder (CGD), a rare blood condition that stops his immune system working properly; causing him repeated bouts of serious infection. He shares his personal journey through a bone marrow transplantation to cure him of this life-threatening condition. Keywords: genes, genetics, DNA, genetic disorder, chronic granulomatous disorder, bone marrow transplant Subject links: PSHE, Science, Biology Curriculum links – KS3: conception, growth, development, behaviour and health can be affected by diet, drugs and disease. Theses resources are from Genetic Disorders UK, which provides schools with a host of free resources for increasing awareness and understanding of genetic disorders.

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Treating Genetic Conditions

This is a simple activity to introduce genetic conditions and how gene therapy is being developed to try to treat them. Students model the chromosomes in a nucleus and investigate the idea of gene transfer, before answering questions on a worksheet. This worksheet is part of a collection of materials based on...

Introducing DNA *suitable for home teaching*

This worksheet introduces inheritance and the basic structure and function of DNA, including the genetic code and the idea that genetic conditions can be caused by changes in the code. The resource also looks at what the DNA of different species can tell us about evolution and our ancestors. This worksheet is part...

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